CCVs & ICVs
Send us Fan MailThis week on Bench Boost Mike explains two key ICP-OES/ICP-MS quality control samples: the Initial Calibration Verification (ICV) and Continuing Calibration Verification (CCV). The ICV is run after calibr...
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Elevated ICP-OES Backgrounds
Send us Fan MailThis week Mike discusses elevated backgrounds in ICP-OES when analyzing high total dissolved solids (TDS) samples such as brines, digests, excipients, salts, and starting materials. TDS increases free ele...
Conductivity Tips and Tricks
Send us Fan MailJoin Mike this week on Bench Boost as he explores the basics of conductivity measurements. We review the theory of how conductivity is dependent on ion concentration, charge, and mobility. He describes ho...
Titrations and USP 541
Send us Fan MailThis week on Bench Boost we discuss titration techniques based on USP 541 and the Inorganic Venture's Titration Tips and Tricks guide. Mike explains the difference between equivalence point and observed e...
pH and USP 791
Send us Fan MailThis week on Bench Boost Mike explains why accurate pH measurement is more complex than it appears, highlighting the effects from temperature, ionic strength, calibration technique, probe condition, and s...
Common Tips for Analyzing Low Concentrations
Send us Fan MailThis week on Bench Boost Mike shares practical tips for analyzing pharmaceutical samples at low concentrations for USP 232 elemental impurities, emphasizing that high dilution makes small contamination or...
The J Value
Send us Fan MailThis week Mike and Ashley explain the J value used in pharmaceutical elemental impurity testing to relate typical ICP concentration units to permitted daily exposure (PDE) limits reported in micrograms pe...
Pharma Elemental Analysis Overview
Send us Fan MailThis week Mike & Ashley review the standardized methods for elemental impurity analysis in pharmaceuticals: ICH Q3D, USP , and USP . ICH Q3D provides guidelines for testing up to 24 elements and emphasize...
Tech Support Questions 2
Send us Fan MailThe Inorganic Ventures team members answer more listener questions relevant to trace analysis. They address low mercury recovery at 2 ppb, noting mercury instability in nitric acid, adsorption to plastic,...
Tech Support Questions 1
Send us Fan MailThe Inorganic Ventures team answers listener questions focused on pharmaceutical elemental impurity analysis by ICP-MS. They explain why an indium internal standard becomes unstable in high-pH matrices du...
Troubleshooting Mining Samples Common Causes of Bad Data
Send us Fan MailThis week on Bench Boost Mike, Autumn, Micah, and Josh discuss common ICP-OES/ICP-MS issues in mining analyses and how to troubleshoot them by separating sample-prep from instrument root causes. Key sampl...
How to Validate a New Mining Method for ICP-OES or ICP-MS
Send us Fan MailThis week on Bench Boost Mike, Autumn, and Thomas dive deep into validation procedures for ICP-OES and ICP-MS methods. They discuss the importance of planning validation parameters early, understanding sa...
Avoiding Precipitation During Mining Sample Prep
Send us Fan MailThis week on Bench Boost the team from Inorganic Ventures discusses avoiding precipitation during sample preparation. They review mining sample challenges including high concentrations of Ca, Fe, Al, & si...
Collision Reaction Cell ICPMS for Mining Applications
Send us Fan MailThis week on Bench Boost on team spotlights mining analysis challenges on ICP-MS due to high total dissolved solids, aggressive digestions, and low-ppb targets requiring interference control. They review ...
ICP Considerations for Lithium
Send us Fan MailThis week on Bench Boost our team reviews special considerations for measuring lithium by ICP-OES and ICP-MS. They discuss common lithium sample types and preparation guidance. Autumn emphasizes the impac...
Method Detection Limits in Mining: Why MDLs are Higher than You Expect
Send us Fan MailIn this episode of Bench Boost our team revisits method detection limits (MDLs) with a focus on why mining applications often produce higher MDLs than expected. Autumn contrasts instrument detection limit...
Axial vs Radial ICP-OES for Mining
Send us Fan MailIn this episode of Bench Boost, Mike, Autumn, and Thomas discuss the differences between axial and radial views when using ICP-OES instruments. The focus is on how each view will impact precision, sensiti...
Why Cyanide is Used in Mining Complexation Chemistry Simplified
Send us Fan MailIn this episode of Bench Boost our team focuses the discussion on metal cyanide chemistry. The discussion revolves around how cyanide leaching is used in mining for extracting precious metals like gold an...
PGM (Platinum-Group Metals) Samples: Stabilization & Washout Problems on ICP-MS
Send us Fan MailIn this episode of Bench Boost, our team reviews the challenges and solutions related to measuring Platinum Group Metals (PGMs) using ICP Mass Spectrometry (ICP-MS). We discuss issues like signal stabiliz...
REE Rich Ores: What Makes Rare Earth Digestion and Analysis Unique?
Send us Fan MailIn this episode of Bench Boost our team discuss the intricacies of digesting and analyzing rare earth element ore samples. This week we cover challenges such as complex spectra, reaction chemistry, and th...